Protonation and geometry of histidine rings
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چکیده
منابع مشابه
Histidine protonation and the activation of viral fusion proteins.
Many viral fusion proteins only become activated under mildly acidic condition (pH 4.5-6.5) close to the pK(a) of histidine side-chain protonation. Analysis of the sequences and structures of influenza HA (haemagglutinin) and flaviviral envelope glycoproteins has led to the identification of a number of histidine residues that are not only fully conserved themselves but have local environments ...
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Plastocyanin is a small blue copper protein that shuttles electrons as part of the photosynthetic redox chain. Its redox behavior is changed at low pH as a result of protonation of the solvent-exposed copper-coordinating histidine. Protonation and subsequent redox inactivation could have a role in the down regulation of photosynthesis. As opposed to plastocyanin from other sources, in fern plas...
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The energetic fitness of histidine in each of its three protonation states has been investigated for NMRdetermined protein structures by using molecular mechanics calculations. The protein structures have been taken from the Protein Data Bank (PDB). For the proteins in the database, we generated all isomers, considering all combinations of protonation forms of each histidine. The energy of each...
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The formation constants of the species formed in the systems H+ + Mo(VI) + histidine and H+ +histidine have been determined at different aqueous solutions of methanol (0 - 45 % v/v) at 25 °C andconstant ionic strength (0.1 mol dm-3 sodium perchlorate), using a combination of spectrophotometricand potentiometric techniques. The composition of the complex species was determined by thecontinuous v...
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I. BASIC TOOL: RATIONAL PARAMETRIZATION Algebraic geometry is a generalization of analytic geometry the familiar study of lines, planes, circles, parabolas, ellipses, hyperbolas, and their 3 dimensional versions: spheres, cones, hyperboloids, ellipsoids, and hyperbolic surfaces. The essential common property these all have is that they are defined by polynomials. This is the defining characteri...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section D Biological Crystallography
سال: 2015
ISSN: 1399-0047
DOI: 10.1107/s1399004715007816